DMEK (Descemet Membrane Endothelial Keratoplasty)

The cornea is the crystal clear window in the front of the eye.









If a cornea is no longer able to adequately accomplish one or more its functions (transparency, focused imaging, stability), the only available help is the tranplantation of a clear human cornea. A corneal transplantation can be performed full thickness or partial thickness (lamellar).

Corneal transplantation













DMEK is a partial-thickness cornea transplant procedure that involves selective removal of the deep layers (Descemet membrane and endothelium) of the cornea, followed by transplantation of donor corneal endothelium and Descemet membrane.
A clear corneal incision is created, the recipient endothelium and Descemet membrane are removed, and the graft is loaded into an inserter. After injecting the tissue into the anterior chamber, the surgeon orients and unscrolls the graft, and a bubble of 20% sulfur hexafluoride (SF6) gas is placed in the anterior chamber to support graft adherence.
The indications for DMEK are endothelial diseases such as dystrophies, pseudophakic bullous keratopathy, ICE syndrome, and other causes of corneal endothelial dysfunction.
DMEK offers the most rapid visual rehabilitation of any keratoplasty technique to date. Final visual acuity can be outstanding due to minimal optical interface effects. Because less tissue is transplanted, there is a lower risk of allograft rejection and less long-term relianceon topical steroids compared with other types of keratoplasty.











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